The substantiation of the composition of a soft medicine for the therapy of inflammatory diseases of the musculoskeletal system

Aim. To substantiate the optimal composition of base semisolid dosage form with thick extract feverfew (Tanacetum parthebased on structural-mechanical, textural, adhesive and microscopic studies. Materials methods. The study objects were samples a various gelling agents reference drug “Irikar”. In course research, complex structural-mechanical methods analysis used. Results discussion. studies properties have determined regularities in rheological characteristics experimental made using different agents. It has been found that rheogram emulgel sample smooth transition from elastic deformation region to elastic-plastic one, which may indicate more homogeneous distribution components. also corresponds textural refenium) rence – “Irikar” cream. substantiated rational content agent 3 %. results confirmed by data Conclusions. obtained are basis for further pharmaceutical development Tanacetum parthenium treatment diseases musculoskeletal system.